2-Methoxyethanol as an alternative reaction solvent for the synthesis of 1,5-benzodiazepines under microwave irradiation

oleh: Sainath B. Zangade, Shyam Mokle, Shivaji Chavan, Yeshwant B Vibhute

Format: Article
Diterbitkan: Universidade Federal de Mato Grosso do Sul 2011-12-01

Deskripsi

<div>An improved condensation reaction between substituted 2’-hydroxychalcones and o-phenylenediamine using piperidine in 2-methoxyetahnol as an efficient and alternative reaction medium. The clean reaction conditions, easy work up, time saving and higher yields are notable advantages of present method.</div>