Radical aryl migration enables diversity-oriented synthesis of structurally diverse medium/macro- or bridged-rings
oleh: Lei Li, Zhong-Liang Li, Fu-Li Wang, Zhen Guo, Yong-Feng Cheng, Na Wang, Xiao-Wu Dong, Chao Fang, Jingjiang Liu, Chunhui Hou, Bin Tan, Xin-Yuan Liu
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-12-01 |
Deskripsi
Medium-sized ring systems are common in natural products, however their synthesis is challenging, largely due to entropic factors. Here the authors report a radical-based method for the synthesis of medium to large functionalized, carbon or heterocyclic scaffolds.