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Background: The current study was aimed to evaluate the antibacterial and antioxidant activities of some Saudi Arabia honey products. Materials & Methods: For this investigation, sixty Saudi Arabia honey products were tested to determine the antimicrobial activity against highly antibiotic-resistant pathogens as well as antioxidant activity in comparison with Manuka honey as a standard. Results: Testing Saudi Arabia honeys, different levels of growth suppression were observed against five bacterial strains. The pathogenic strains were Staphylococcus aureusas, Escherichia coli, Proteus vulgaris, Citrobacter diversus and Salmonella enterica. These suppression levels depended on the type of honey. The comparative study of Saudi Arabia honeys revealed a strong correlation between total polyphenol and flavonoid contents and significant radical scavenging activities. Conclusion:  It was concluded that Saudi Arabia honey products have the capacity to suppress the growth of pathogenic bacteria and perform significant radical scavenging activities.