Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite

oleh: Tommi Kotila, Hugo Wioland, Muniyandi Selvaraj, Konstantin Kogan, Lina Antenucci, Antoine Jégou, Juha T. Huiskonen, Guillaume Romet-Lemonne, Pekka Lappalainen

Format: Article
Diterbitkan: Nature Portfolio 2022-06-01

Deskripsi

The authors report here the structure-function analysis of highly divergent actin from Leishmania parasite. The study reveals remarkably rapid dynamics of parasite actin as well as the underlying molecular basis, thus providing insight into evolution of the actin cytoskeleton.