Natterin-like depletion by CRISPR/Cas9 impairs zebrafish (Danio rerio) embryonic development
oleh: Ana Carolina Seni-Silva, Adolfo Luis Almeida Maleski, Milena Marcolino Souza, Maria Alice Pimentel Falcao, Geonildo Rodrigo Disner, Monica Lopes-Ferreira, Carla Lima
| Format: | Article |
|---|---|
| Diterbitkan: | BMC 2022-02-01 |
Deskripsi
Highlights The Natterin family was discovered in the venom of the fish Thalassophryne nattereri. The zebrafish genome encodes eleven natterin-like genes. Natterin-like might be a novel fish-specific defense molecule. Natterin-like proteins are thought to be pore-forming molecules. Reverse genetic study and phenotypic characterization suggests natterin-like genes may have roles in zebrafish development.