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Bodiniosides S–Y, Seven New Triterpenoid Saponins from <i>Elsholtzia bodinieri</i> and Their Anti-Influenza Activities
oleh: Linyao Yang, Jiangchao Du, Rongtao Li, Fei Yu, Jindong Zhong
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2021-10-01 |
Deskripsi
Investigation of the n-BuOH extract of the aerial parts of <i>Elsholtzia bodinieri</i> led to the isolation of seven new triterpenoid saponins, Bodiniosides S–Y (<b>1</b>–<b>7</b>, resp.). Their strictures were elucidated on the basis of spectroscopic techniques, including HSQC, HSBC, and HSQC–TOCSY experiments, together with acid hydrolysis and GC analysis. The anti-influenza activities of compounds <b>1</b>–<b>7</b> were evaluated against A/WSN/33/2009 (H1N1) virus in MDCK cells. The results showed that compounds <b>2</b> and <b>5</b> exhibited moderate anti-influenza activities against A/WSN/33/2009 (H1N1), with inhibition rates of 35.33% and 24.08%, respectively.