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Objective: To compare the impact of polyglactin 910 (1-0) (Vicryl rapide) (VR) and Chromic Catgut (1-0) (CC) sutures on perineal pain in walking, sitting, and lying posture at 24 h, 48 h, and 6 weeks after episiotomy wound repair. Materials and Methods: Patients were divided randomly into two groups: VR group and CC group. Each group consisted of 50 patients. Severity of the pain was assessed by the visual analogue scale and by the requirement of analgesics. Ordinal data were analyzed by Mann-Whitney U-test. Categorical data were analyzed by Chi-square test. Results: Compared to CC, VR produced significantly less pain (P < 0.001) among patients following episiotomy wound repair in walking, sitting, and lying posture at 24 h, 48 h, and 6 weeks postpartum. Conclusion: Perineal repair with VR suture is associated with less pain perception compared to CC suture.