ASXL1 mutations in younger adult patients with acute myeloid leukemia: a study by the German-Austrian Acute Myeloid Leukemia Study Group

oleh: Peter Paschka, Richard F. Schlenk, Verena I. Gaidzik, Julia K. Herzig, Teresa Aulitzky, Lars Bullinger, Daniela Späth, Veronika Teleanu, Andrea Kündgen, Claus-Henning Köhne, Peter Brossart, Gerhard Held, Heinz-A. Horst, Mark Ringhoffer, Katharina Götze, David Nachbaur, Thomas Kindler, Michael Heuser, Felicitas Thol, Arnold Ganser, Hartmut Döhner, Konstanze Döhner

Format: Article
Diterbitkan: Ferrata Storti Foundation 2015-03-01

Deskripsi

We studied 1696 patients (18 to 61 years) with acute myeloid leukemia for ASXL1 mutations and identified these mutations in 103 (6.1%) patients. ASXL1 mutations were associated with older age (P