Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages

oleh: Stefan Schoenfelder, Borbala Mifsud, Claire E. Senner, Christopher D. Todd, Stephanie Chrysanthou, Elodie Darbo, Myriam Hemberger, Miguel R. Branco

Format: Article
Diterbitkan: Nature Portfolio 2018-10-01

Deskripsi

The role of the genome structure in the establishment of the embryonic and trophoblast lineages is still not well understood. Here the authors perform promoter capture Hi-C in mouse trophoblast and embryonic stem cells and find divergent networks of repressive and active chromatin interactions between the two lineages.