Ubiquitination of CLIP-170 family protein restrains polarized growth upon DNA replication stress
oleh: Xi Wang, Fan Zheng, Yuan-yuan Yi, Gao-yuan Wang, Li-xin Hong, Dannel McCollum, Chuanhai Fu, Yamei Wang, Quan-wen Jin
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-09-01 |
Deskripsi
The microtubule plus-end tracking protein Tip1 regulates microtubule dynamics and polar growth in fission yeast. Here the authors link the ubiquitination of Tip1 by ubiquitin ligase Dma1 to polarized growth inhibition upon DNA replication stress.