CircAnks1a in the spinal cord regulates hypersensitivity in a rodent model of neuropathic pain
oleh: Su-Bo Zhang, Su-Yan Lin, Meng Liu, Cui-Cui Liu, Huan-Huan Ding, Yang Sun, Chao Ma, Rui-Xian Guo, You-You Lv, Shao-Ling Wu, Ting Xu, Wen-Jun Xin
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-09-01 |
Deskripsi
Circular RNAs are non-coding RNAs that are enriched in the CNS, but their role in chronic pain is not known. Here the authors show that CircAnks1a in dorsal horn neurons contributes to pain-like hypersensitivity in a rodent model of neuropathic pain, via a VEGF mechanism.