Successful infusional 5-fluorouracil administration in a patient with vasospastic angina
oleh: Shannon Tai, Divyanshu Mohananey, Claire Griffiths, Bradley Johnson, Jalaj Garg, Timothy J. Ridolfi, Nicole L. Lohr, Sakti Chakrabarti, Sherry-Ann Brown
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2022-05-01 |
Deskripsi
A 48-year-old female with metastatic colon adenocarcinoma and history of pre-existing coronary vasospasm with ventricular tachycardia (VT) successfully tolerated de novo 5-fluorouracil (5-FU) chemotherapy infusions with prophylactic administration and optimization of anti-spasm medications. 5-FU has been reported to produce severe cardiotoxic side effects, including coronary vasospasm, ventricular arrhythmias, and sudden cardiac death, and is not typically reported in individuals with pre-existing coronary vasospasm.