Delayed postoperative radiation therapy in local control of squamous cell carcinoma of the tongue and floor of the mouth
oleh: Ali Amar, Helma Maria Chedid, Otávio Alberto Curioni, Rogério Aparecido Dedivitis, Abrão Rapoport, Claudio Roberto Cernea, Lenine Garcia Brandão
| Format: | Article |
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| Diterbitkan: | Instituto Israelita de Ensino e Pesquisa Albert Einstein |
Deskripsi
Objective To evaluate the effect of time between surgery and postoperative radiation therapy on local recurrence of squamous cell carcinoma of the tongue and floor of the mouth.Methods A total of 154 patients treated between 1996 and 2007 were selected considering local recurrence rate and time of the adjuvant radiotherapy.Results Local recurrence was diagnosed in 54 (35%) patients. Radiation therapy reduced the rate of local recurrences, although with no statistical significance. The time between surgery and initiation of postoperative radiotherapy did not significantly influence the risk of local recurrence in patients referred to adjuvant treatment (p=0.49).Conclusion In the presence of risk factors for local recurrence, a short delay in starting the adjuvant radiation therapy does not contraindicate its performance.