A multiplexable TALE-based binary expression system for in vivo cellular interaction studies

oleh: Markus Toegel, Ghows Azzam, Eunice Y. Lee, David J. H. F. Knapp, Ying Tan, Ming Fa, Tudor A. Fulga

Format: Article
Diterbitkan: Nature Portfolio 2017-11-01

Deskripsi

Binary expression systems enable researchers to deliver loss-of-function or gain-of-function transgenes with spatial-temporal resolution in vivo. Here, the authors present a programmable TALE-based system for multiplexed orthogonal activation of transgenes in Drosophila.