Regulation of Notch output dynamics via specific E(spl)-HLH factors during bristle patterning in Drosophila
oleh: Lydie Couturier, Khalil Mazouni, Francis Corson, François Schweisguth
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-08-01 |
Deskripsi
The patterning of sensory bristles on the dorsal thorax of flies is regulated by two transcription factor families but the dynamics of this regulation is unclear. Here, the authors visualize seven E(spl)-HLH proteins, showing their regulated expression promotes mutual inhibition by Notch during notum patterning.