Water-organizing motif continuity is critical for potent ice nucleation protein activity

oleh: Jordan Forbes, Akalabya Bissoyi, Lukas Eickhoff, Naama Reicher, Thomas Hansen, Christopher G. Bon, Virginia K. Walker, Thomas Koop, Yinon Rudich, Ido Braslavsky, Peter L. Davies

Format: Article
Diterbitkan: Nature Portfolio 2022-08-01

Deskripsi

Ice nucleation proteins have the same tandemly arrayed water-organizing motifs seen in some antifreeze proteins, but on a larger scale. The authors show that mutation, interruption, and truncation of these arrays reduce ice nucleation activity indicating that the two protein types share a common mechanism.