Uncovering the SUMOylation and ubiquitylation crosstalk in human cells using sequential peptide immunopurification
oleh: Frédéric Lamoliatte, Francis P. McManus, Ghizlane Maarifi, Mounira K. Chelbi-Alix, Pierre Thibault
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-01-01 |
Deskripsi
Ubiquitylation and SUMOylation are two important related post-translational modifications. Here the authors present an approach for the simultaneous identification and quantification of protein-wide SUMO and ubiquitin sites from a single sample, uncovering widespread crosstalk between the two modifications.