Disordered actomyosin networks are sufficient to produce cooperative and telescopic contractility
oleh: Ian Linsmeier, Shiladitya Banerjee, Patrick W. Oakes, Wonyeong Jung, Taeyoon Kim, Michael P. Murrell
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-08-01 |
Deskripsi
The interaction between myosin motors and F-actin is well described, but the impact of actin organization on contractility is not well described. Here the authors use a 2D biomimetic system and computational modelling to show that contractility of isotropic actomyosin is cooperative, and contraction velocity scales with myosin activation area.