Modulation of Hoogsteen dynamics on DNA recognition

oleh: Yu Xu, James McSally, Ioan Andricioaei, Hashim M. Al-Hashimi

Format: Article
Diterbitkan: Nature Portfolio 2018-04-01

Deskripsi

DNA is found in a dynamic equilibrium between standard Watson-Crick (WC) base pairs and non-standard Hoogsteen (HG) base pairs. Here the authors describe the influence of echinomycin and actinomycin D ligands binding on the HG-WC base pair dynamics in DNA.