Cryo-EM structure of lysenin pore elucidates membrane insertion by an aerolysin family protein
oleh: Monika Bokori-Brown, Thomas G. Martin, Claire E. Naylor, Ajit K. Basak, Richard W. Titball, Christos G. Savva
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-04-01 |
Deskripsi
Lysenin is member of the aerolysin family of small ß-barrel pore-forming toxins that include virulence factors from several human and animal pathogens. Here the authors determine the structure of the lysenin pore by single particle cryo- EM and propose a conserved pore formation mechanism for the aerolysin protein family.