Cryo-EM structure supports a role of AQP7 as a junction protein

oleh: Peng Huang, Raminta Venskutonytė, Rashmi B. Prasad, Hamidreza Ardalani, Sofia W. de Maré, Xiao Fan, Ping Li, Peter Spégel, Nieng Yan, Pontus Gourdon, Isabella Artner, Karin Lindkvist-Petersson

Format: Article
Diterbitkan: Nature Portfolio 2023-02-01

Deskripsi

Glycerol flux across the plasma membrane is critical to metabolism and linked to disease. Here, authors present the cryo-EM structure of the glycerol channel AQP7 composed of two adhering tetramers and displaying well-defined densities in the central pore.