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Iron-catalyzed synthesis of N-heterocycles via intermolecular and intramolecular cyclization reactions: A review
oleh: Maria Sohail, Muhammad Bilal, Tahir Maqbool, Nasir Rasool, Muhammad Ammar, Sajid Mahmood, Ayesha Malik, Muhammad Zubair, Ghulam Abbas Ashraf
Format: | Article |
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Diterbitkan: | Elsevier 2022-09-01 |
Deskripsi
Small N-heterocyclic molecules are important scaffolds in the pharmaceutical industry and most FDA-approved drugs are nitrogen-containing heterocycles. Chemists try to employ iron-based catalysts for organic transformations due to their abundance, economic, easily accessible and environment-friendly behaviour. N-heterocycles are synthesized by the cyclization reactions. This review covered the synthesis of N-heterocycles by employing iron-based catalysts via intermolecular or intramolecular cyclizations.