ERK 1/2 activation does not contribute to increased survival mediated by bone marrow cells after 90% partial hepatectomy in Wistar rats

oleh: Gustavo Alfredo Ochs de Muñoz, Nelson Alexandre Kretzmann, Mónica Luján López, Carlos Oscar Kieling, Carolina Uribe-Cruz, Luciano Basso da Silva, Alessandro Bersch Osvaldt, Ursula da Silveira Matte

Format: Article
Diterbitkan: Hospital de Clinicas de Porto Alegre ; Universidade Federal do Rio Grande do Sul (UFRGS) 2017-01-01

Deskripsi

We investigated the influence of bone marrow cells upon activation of ERK ½ in an animal model of 90% PH. Phosphorylated ERK 1/2 was evaluated by western blot. No differences were found between the groups. Thus, increased survival does not appear to be mediated by ERK 1/2 activation. Keywords: MAP Kinase Signaling System; stem cells; acute liver failure