Bacterial outer membrane vesicle based versatile nanosystem boosts the efferocytosis blockade triggered tumor-specific immunity
oleh: Wan-Ru Zhuang, Yunfeng Wang, Weidong Nie, Yao Lei, Chao Liang, Jiaqi He, Liping Zuo, Li-Li Huang, Hai-Yan Xie
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-03-01 |
Deskripsi
Efferocytosis inhibition leads to the release of immunogenic contents into the tumor microenvironment. Here the authors developed a nanosystem that inhibits MerTK-mediated efferocytosis and captures tumor-associated agents to enhance antitumour immunity.