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The nuclear functions of long noncoding RNAs come into focus
oleh: Zhenxing Song, Jiamei Lin, Zhengguo Li, Chuan Huang
Format: | Article |
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Diterbitkan: | KeAi Communications Co., Ltd. 2021-06-01 |
Deskripsi
Long noncoding RNAs (lncRNAs), defined as untranslated and tightly-regulated transcripts with a length exceeding 200 nt, are common outputs of the eukaryotic genome. It is becoming increasingly apparent that many lncRNAs likely serve as important regulators in a variety of biological processes. In particular, some of them accumulate in the nucleus and function in diverse nuclear events, including chromatin remodeling, transcriptional regulation, RNA processing, DNA damage repair, etc. Here, we unite recent progresses on the functions of nuclear lncRNAs and provide insights into the future research directions of this field.