NirA Is an Alternative Nitrite Reductase from Pseudomonas aeruginosa with Potential as an Antivirulence Target
oleh: Samuel Fenn, Jean-Frédéric Dubern, Cristina Cigana, Maura De Simone, James Lazenby, Mario Juhas, Stephan Schwager, Irene Bianconi, Gerd Döring, Jonas Elmsley, Leo Eberl, Paul Williams, Alessandra Bragonzi, Miguel Cámara
| Format: | Article |
|---|---|
| Diterbitkan: | American Society for Microbiology 2021-04-01 |
Deskripsi
The emergence of widespread antimicrobial resistance has led to the need for development of novel therapeutic interventions. Antivirulence strategies are an attractive alternative to classic antimicrobial therapy; however, they require identification of new specific targets which can be exploited in drug discovery programs.