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Transplantation provides a near normal life and excellent rehabilitation compared to dialysis and is the pre-ferred method oftreatment for end stage renal disease patients. We describe our experiences through a retrospec-tive analysis ol′anaesthesia management of 350 cases of both living related and cadaveric renal transplantation conducted between Jan 2004 -April 2008 at Jaslok Hospital And Research Center. Areas ol′our interest include preoperative patient status, fluid management, hemodynamic stability, anaesthesia management, and perioperative complications. Recent advances in surgical techniques; anaesthesia management and immunosuppressive drugs have made renal transplantation sale and predictable. Preoperative patient optimization, intraoperative physiologi-cal stability and postoperative care of′renal transplant patients have contributed to the success of′renal transplant programme in our hospital.