Global pairwise RNA interaction landscapes reveal core features of protein recognition

oleh: Qin Zhou, Nikesh Kunder, José Alberto De la Paz, Alexandra E. Lasley, Vandita D. Bhat, Faruck Morcos, Zachary T. Campbell

Format: Article
Diterbitkan: Nature Portfolio 2018-06-01

Deskripsi

RNA–protein interactions often depend on the recognition of extended RNA elements but the identification of these motifs is challenging. Here, the authors present a global integrated approach to analyze RNA–protein binding landscapes, mapping extended RNA interaction motifs for four RNA-binding proteins.