High-throughput chromatin accessibility profiling at single-cell resolution

oleh: Anja Mezger, Sandy Klemm, Ishminder Mann, Kara Brower, Alain Mir, Magnolia Bostick, Andrew Farmer, Polly Fordyce, Sten Linnarsson, William Greenleaf

Format: Article
Diterbitkan: Nature Portfolio 2018-09-01

Deskripsi

Single-cell chromatin accessibility is a promising means to identify regulatory programs in mixtures of cells. Here the authors describe ยต-ATAC-seq, a low-cost method that can generate thousands of accessibility profiles per day.