An efficient approach for the total synthesis of sumalactone A
oleh: Rajashekar Reddy Nimmaredddy, Himabindu Gandham, *, Janardana Reddi Desireddi, Sudheer Reddy Vootukoori, A. Venkatram Reddy, Kiran Kumar Murahari, Krishnakanth Reddy Leleti
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2023-12-01 |
Deskripsi
Sumalactone A, a 10-membered Benzannulated macrolactone, was synthesised in a straightforward and efficient stereoselective manner using affordable and readily accessible starting materials. The main steps in this convergent synthesis are Vilsmeier-Haack formylation, Grignard reaction, alkylation of 1,3-dithiane and Yamaguchi macrolactonization.