Sox17 is required for endothelial regeneration following inflammation-induced vascular injury
oleh: Menglin Liu, Lianghui Zhang, Glenn Marsboom, Ankit Jambusaria, Shiqin Xiong, Peter T. Toth, Elizaveta V. Benevolenskaya, Jalees Rehman, Asrar B. Malik
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-05-01 |
Deskripsi
Endothelial cell regeneration is essential for blood vessels to recover from inflammation-induced injury. Here Liu et al. show that the transcription factor Sox17 is required for endothelial regeneration following endotoxemia, and that delivery of a transgene expressing Sox17 to lung endothelial cells enhances recovery after injury.