Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction

oleh: Florian Fäßler, Georgi Dimchev, Victor-Valentin Hodirnau, William Wan, Florian K. M. Schur

Format: Article
Diterbitkan: Nature Portfolio 2020-12-01

Deskripsi

The actin-related protein (Arp)2/3 complex nucleates branched actin filament networks pivotal for cell migration, endocytosis and pathogen infection. Here, authors report a 9.0 Å resolution structure of the actin filament Arp2/3 complex branch junction in cells using cryo-electron tomography and subtomogram averaging.