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Due to a shift in the competitive environment, the global fine chemicals industry is in the center of a major portfolio change from high-volume raw materials to customer-specific molecules. This article describes how the traditional strength in chemistry and adaptation of business processes throughout the organization allows Clariant Fine Chemicals to play a major role as a supplier of advanced building blocks to the life science industry. Key criteria are identification of intermediates according to core technologies, installation of flexible production equipment, production in line with strict quality standards, and efficient exchange of information in strict confidence to establish a basis for mutual success between Clariant and its customers.