skater: an R package for SNP-based kinship analysis, testing, and evaluation [version 1; peer review: 2 approved, 1 approved with reservations]

oleh: Bruce Budowle, Carlos Acevedo, Shakeel Jessa, August E. Woerner, Jianye Ge, Stephen D. Turner, Matthew Scholz, V.P. Nagraj

Format: Article
Diterbitkan: F1000 Research Ltd 2022-01-01

Deskripsi

Motivation: SNP-based kinship analysis with genome-wide relationship estimation and IBD segment analysis methods produces results that often require further downstream process- ing and manipulation. A dedicated software package that consistently and intuitively imple- ments this analysis functionality is needed. Results: Here we present the skater R package for SNP-based kinship analysis, testing, and evaluation with R. The skater package contains a suite of well-documented tools for importing, parsing, and analyzing pedigree data, performing relationship degree inference, benchmarking relationship degree classification, and summarizing IBD segment data. Availability: The skater package is implemented as an R package and is released under the MIT license at https://github.com/signaturescience/skater. Documentation is available at https://signaturescience.github.io/skater.