An engineered thermal-shift screen reveals specific lipid preferences of eukaryotic and prokaryotic membrane proteins

oleh: Emmanuel Nji, Yurie Chatzikyriakidou, Michael Landreh, David Drew

Format: Article
Diterbitkan: Nature Portfolio 2018-10-01

Deskripsi

Membrane bilayers are made up of a myriad of different lipids that affect membrane proteins, but identifying those specific lipid requirements remains a challenge. Here authors present an engineered thermal-shift screen which reveals specific lipid preferences of eukaryotic and prokaryotic membrane proteins.