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Highly-sensitive label-free deep profiling of N-glycans released from biomedically-relevant samples
oleh: Anne-Lise Marie, Somak Ray, Alexander R. Ivanov
Format: | Article |
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Diterbitkan: | Nature Portfolio 2023-03-01 |
Deskripsi
Glycans can serve as disease biomarkers. Here, the authors use label-free capillary electrophoresis-mass spectrometry for N-glycan profiling of minute sample amounts, resolving and characterizing previously undetected highly sialylated glycans and linkage isomers in a single analysis.