Highly-sensitive label-free deep profiling of N-glycans released from biomedically-relevant samples

oleh: Anne-Lise Marie, Somak Ray, Alexander R. Ivanov

Format: Article
Diterbitkan: Nature Portfolio 2023-03-01

Deskripsi

Glycans can serve as disease biomarkers. Here, the authors use label-free capillary electrophoresis-mass spectrometry for N-glycan profiling of minute sample amounts, resolving and characterizing previously undetected highly sialylated glycans and linkage isomers in a single analysis.