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Antimicrobial Resistance Patterns in Diabetic Foot Infections, an Epidemiological Study in Northeastern Italy
oleh: Giovanni Boschetti, Dino Sgarabotto, Marco Meloni, Marino Bruseghin, Christine Whisstock, Mariagrazia Marin, Sasa Ninkovic, Michela Pinfi, Enrico Brocco
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2021-10-01 |
Deskripsi
This study is a retrospective epidemiological assessment of bacterial species isolated from a cohort of out-patients with diabetic foot infections referred to our “Diabetic Foot Unit” over one year, with particular attention to index pathogens, as identified by the EARS Network. <i>Staphylococcus aureus</i> and <i>Pseudomonas aeruginosa</i> accounted for 33.5% and 11.9% of cases, respectively. <i>MRSA</i> was isolated in 27.1% of patients, with 14.06% showing additional resistance to three antimicrobial classes. <i>Pseudomonas aeruginosa</i> presented extensive resistance to fluoroquinolones (57.3%), which was associated with resistance to piperacillin in 17.6% or to carbapenems in 23.5% of cases. Other pathogens, such as <i>methicillin resistant</i><i>Staphylococcus epidermidis</i>, <i>Escherichia coli</i> and <i>Morganella morganii</i> ESBL and <i>Enterococcus faecium</i> VRE, were also found.