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With fatty acid and amino acid as raw materials, the neutral medium inhibitor was synthesized. The inhibitory performance of corrosion inhibitor for corrosion of Q235 steel in neutral water medium was investigated by weight loss method. Results showed that the inhibitor has excellent inhibition efficiency for corrosion of Q235 steel in neutral water medium; the inhibition efficiency increased with increase in inhibitor concentration, and then tend to be stable due to the inhibitors come to adsorption equilibrium in the metal surface. Using scanning electron microscope (SEM) to observe the micro corrosion morphology, and the corrosion mechanism is discussed in this article.