Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox
oleh: Zhen-Xing Wang, Zhong-Wei Luo, Fu-Xing-Zi Li, Jia Cao, Shan-Shan Rao, Yi-Wei Liu, Yi-Yi Wang, Guo-Qiang Zhu, Jiang-Shan Gong, Jing-Tao Zou, Qiang Wang, Yi-Juan Tan, Yan Zhang, Yin Hu, You-You Li, Hao Yin, Xiao-Kai Wang, Ze-Hui He, Lu Ren, Zheng-Zhao Liu, Xiong-Ke Hu, Ling-Qing Yuan, Ran Xu, Chun-Yuan Chen, Hui Xie
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2022-03-01 |
Deskripsi
This study uncovers the role of extracellular vesicles from bone matrix as a messenger in the development of osteoporosis and vascular calcification (calcification paradox) during skeletal aging and menopause by transferring miR-483-5p and miR-2861.