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Schizophrenia is a severe mental disorder that includes behavioural and cognitive manifestations generated by genetic or environmental factors, caused by a dysfunction of the dopaminergic system which contributes to the genesis of psychosis, producing a profound effect on affected individuals and society [6]. In this work, demographic data, neuropsychological profiles and measurements of brain morphometry, using Magnetic Resonance Image (MRI), of three groups of patients are presented. A control group with 15 patients, a schizophrenic without dementia group with 10 patients, and a schizophrenic with dementia group with 10 patients constituted the observed sample. Results of 21 neuropsychological tests and 11 brain structure measurements are included. The data set is a comprehensive source for advancing in a further understanding of schizophrenia and schizophrenia-dementia neuro-pathologies.