Alteration in tyrosine phosphorylation of cardiac proteome and EGFR pathway contribute to hypertrophic cardiomyopathy
oleh: Mingguo Xu, Kevin C. Bermea, Marzieh Ayati, Han Byeol Kim, Xiaomei Yang, Andres Medina, Zongming Fu, Amir Heravi, Xinyu Zhang, Chan Hyun Na, Allen D. Everett, Kathleen Gabrielson, D. Brian Foster, Nazareno Paolocci, Anne M. Murphy, Genaro A. Ramirez-Correa
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-11-01 |
Deskripsi
Quantitative global phosphotyrosine proteomics of two mouse models of hypertrophic cardiomyopathy reveals that tyrosine kinase inhibitors may be a future therapeutic approach for treating hypertrophic cardiomyopathy.