Dysregulated transforming growth factor-beta mediates early bone marrow dysfunction in diabetes
oleh: Jina J. Y. Kum, Christopher J. Howlett, Zia A. Khan
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-10-01 |
Deskripsi
Short-term diabetes in mice suppresses transforming growth factor-beta (TGFB) signalling to enhance adipogenesis in the tibiae marrow mesenchymal progenitor cells. Inhibition of adipogenic differentiation by TGFB is mediated through TAK1.