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Median artery is usually a transient vessel during the embryonic period and may persist in adult life as the persistent median artery (PMA) in the upper limbs. It remains asymptomatic in most people; however, thrombosis leading to features of carpal tunnel syndrome is one of the known complications. We report a case of pseudoaneurysm of PMA following a trivial injury. This case report highlights the importance of being aware of this anatomical variation, to avoid complications during hand surgeries.