The role of the tryptophan-NAD + pathway in a mouse model of severe malnutrition induced liver dysfunction
oleh: Guanlan Hu, Catriona Ling, Lijun Chi, Mehakpreet K. Thind, Samuel Furse, Albert Koulman, Jonathan R. Swann, Dorothy Lee, Marjolein M. Calon, Celine Bourdon, Christian J. Versloot, Barbara M. Bakker, Gerard Bryan Gonzales, Peter K. Kim, Robert H. J. Bandsma
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-12-01 |
Deskripsi
Impaired liver metabolic function is related to mortality in severely malnourished children. Here the authors report a role for the tryptophan-NAD + pathway in reduced hepatic mitochondrial function and liver steatosis in a mouse model of severe malnutrition.