Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy

oleh: Yu-Cheng Su, Pierre-Alain Burnouf, Kuo-Hsiang Chuang, Bing-Mae Chen, Tian-Lu Cheng, Steve R. Roffler

Format: Article
Diterbitkan: Nature Portfolio 2017-06-01

Deskripsi

The majority of treatment options for cancers are ineffective due to limited therapeutic targeting. Here, the authors develop bispecific antibodies that effectively target nanomaterials to triple-negative breast cancer cell receptors and deliver therapeutics leading to inhibition of tumour growth.