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Aspect-level sentiment analysis is a fine-grained sentiment analysis task designed to identify the sentiment polarity of specific target in a sentence. However, this task is rarely used in drug reviews. Some models for this task ignore the impact of target semantics, and others do not perform well because the datasets are relatively smaller. Therefore, we propose a Pretraining and Multi-task learning model based on Double BiGRU (PM-DBiGRU). In PM-DBiGRU, we first use the pretrained weight learned from short text-level drug review sentiment classification task to initialize related weight of our model. Then two BiGRU networks are applied to generate the bidirectional semantic representations of the target and drug review, and attention mechanism is used to obtain the target-specific representation for aspect-level drug review. The multi-task learning is further utilized to transfer the helpful domain knowledge from the short text-level drug review corpus. We also propose a dataset SentiDrugs for aspect-level drug review sentiment classification, in which each review may contain one or more targets. Experimental results on SentiDrugs demonstrate that our approach can improve the performance of aspect-level drug reviews sentiment classification compared with other state-of-the-art architectures.