ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling
oleh: Xiaoyun Sun, Xixia Peng, Yuqin Cao, Yan Zhou, Yuhua Sun
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-06-01 |
Deskripsi
ADNP has been connected to neural developmental disorders. Here, the authors uncover a role for ADNP in neural induction and differentiation via β-Catenin stabilization, with ADNP disruption in zebrafish leading to defective neurogenesis and decreased Wnt signaling.