Screening microbially produced Δ9-tetrahydrocannabinol using a yeast biosensor workflow

oleh: William M. Shaw, Yunfeng Zhang, Xinyu Lu, Ahmad S. Khalil, Graham Ladds, Xiaozhou Luo, Tom Ellis

Format: Article
Diterbitkan: Nature Portfolio 2022-09-01

Deskripsi

Microbial production of cannabinoids promises a cheaper and more sustainable route to these important therapeutic molecules, but strain improvement and screening is challenging. Here, the authors develop a yeast-based Δ9-tetrahydrocannabinol (THC) biosensor for screening microbial mutant libraries.