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Precise timing of transcription by c-di-GMP coordinates cell cycle and morphogenesis in Caulobacter
oleh: Andreas Kaczmarczyk, Antje M. Hempel, Christoph von Arx, Raphael Böhm, Badri N. Dubey, Jutta Nesper, Tilman Schirmer, Sebastian Hiller, Urs Jenal
Format: | Article |
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Diterbitkan: | Nature Portfolio 2020-02-01 |
Deskripsi
Bacteria adapt their growth rate to their metabolic status and environmental conditions by modulating the length of their G1 period. Here the authors show that an increase in c-di-GMP concentration modulates the activity of kinase ShkA and transcription factor TacA, thus enabling G1/S transition in Caulobacter.