Precise timing of transcription by c-di-GMP coordinates cell cycle and morphogenesis in Caulobacter

oleh: Andreas Kaczmarczyk, Antje M. Hempel, Christoph von Arx, Raphael Böhm, Badri N. Dubey, Jutta Nesper, Tilman Schirmer, Sebastian Hiller, Urs Jenal

Format: Article
Diterbitkan: Nature Portfolio 2020-02-01

Deskripsi

Bacteria adapt their growth rate to their metabolic status and environmental conditions by modulating the length of their G1 period. Here the authors show that an increase in c-di-GMP concentration modulates the activity of kinase ShkA and transcription factor TacA, thus enabling G1/S transition in Caulobacter.