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Treatment of severe hypertension during pregnancy: we still do not know what the best option is
oleh: Dagmar Wertaschnigg, Rui Wang, Maya Reddy, Fabricio Da Silva Costa, Ben Willem J. Mol, Daniel L. Rolnik
| Format: | Article |
|---|---|
| Diterbitkan: | Taylor & Francis Group 2020-01-01 |
Deskripsi
Intracranial hemorrhage and stroke are primary causes of maternal mortality in pregnancies affected by hypertensive disorders. As such antihypertensive therapy plays a crucial role in the management of severe hypertension. However, the target level to achieve the best outcome for both – mother and fetus – is still unclear. Moreover, given the lack of well-designed randomized controlled trials with standardized key outcomes, the current choice of antihypertensive medications depends rather on clinicians’ preference. Furthermore, data on long-term outcomes of offspring is not available. Therefore, there is an urgent need for randomized trials comparing different anti-hypertensive options to address efficacy and safety questions.